5-Oxo-eicosatetraenoic acid is a Nonclassic eicosanoid metabolite of arachidonic acid and the most potent naturally occurring member of the 5-HETE family of cell signaling agents. 5-(S)-HETE; see 5-HETE) to its 5-keto analog, 5-oxo-eicosatetraenoic acid (i.e. Surrounding the female nipple, areolar glands are specialized sebaceous glands for lubricating the nipple. It is a white flake or powdered solid. Sebacic acid can be used as cold plasticizer, nylon resins and other raw material. A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. Alkyds are used in paints and in moulds for casting. Linear Formula HO 2 C(CH 2) 8 CO 2 H . InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), InChI=1/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), Except where otherwise noted, data are given for materials in their, Ullmann's Encyclopedia of Industrial Chemistry, "Mammalian Wax Biosynthesis II: Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family". CAS 111-20-6, EC Number 203-845-5, chemical formula HOOC(CH₂)₈COOH. Definitions of molecular … 100g; Plastic bottle. 1,10-Decanedioic acid 1,8-Octanedicarboxylic acid Acide sebacique (French) Decanedioic acid n-Decanedioic acid Sebacinsaure (German) USAF HC-1. The SO4 core is a sulfate group and the R group is any organic residue. The salts and esters of stearic acid are called stearates. It is slightly soluble in water, but very soluble in ethanol and ether. It also acts in the reverse direction, metabolizing 5-oxo-ETE to 5(S)-HETE. with 1,6-hexanediamine (1:1) The Molecular Formula is C10H18O4. Sebacic acid is a derivative of castor oil. [3], Sebum is a secretion by skin sebaceous glands. PubChem Substance ID 24857096. Bis(n-butyl)sebacate Decanedioic acid, dibutyl ester Dibutyl sebacate Dibutylester kyseliny sebakove (Czech) Di-n-butyl sebacate Kodaflex DBS In substitutive nomenclature, their names are formed by adding -dioic' as a suffix to the name of the parent compound. Its name comes from the Greek word στέαρ "stéar", which means tallow. nylon 6-10 salt. CDC twenty four seven. Waxes are insoluble in water but soluble in organic, nonpolar solvents. Related Pages. Sebacic acid. 314.52 Molecular Formula. sebacic acid: ChEBI ID CHEBI:41865: Definition An α,ω-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. Sebacic acid. Please see the following for information about the library and its accompanying search program. About 90% of the fatty acid content in castor oil is the triglyceride formed from ricinoleic acid. Line Formula: HOOC(CH 2) 8 COOH Literature References: Obtained on a large scale by heating castor oil or ricinoleic acid with sodium hydroxide. 250°C, so that saponification, leading to the formation of ricinoleic acid; is followed by a reaction giving sebacic acid and octan-2-ol Figure 18.5. Sebacic acid, compd. This saturated dicarboxylic acid exists as a white powder. The equivalent fatty acid in mouse sebum is palmitoleic acid. It has a … Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. Molecular Weight 202.25 . Molecular Weight: 202.25 Molecular Formula: C10H18O4 Additional Metadata. Sebacic acid is also found in other lipids that coat the skin surface. Sebacic acid is produced from castor oil by cleavage of ricinoleic acid, which is obtained from castor oil. Solubility (25°C) In vitro: DMSO ... To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'. Molecular Weight: 202.25 Molecular Formula: C10H18O4 Additional Metadata. 47, 8002h (1953); Dominguez et al., J. Chem. The name can be abbreviated to diacid. Sapienic acid has been implicated in the development of acne, and it may have potent antibacterial activity. May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Waxes are a diverse class of organic compounds that are lipophilic, malleable solids near ambient temperatures. Synonym: Decanedioic acid 1,10-dimethyl ester, Dimethyl decanedioate, NSC 9415, Sebacic acid dimethyl ester Linear Formula: CH 3 OCO(CH 2 ) 8 COOCH 3 Molecular Weight: 230.30 Inhalation Move casualty to fresh air and keep at rest. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Tallow is a rendered form of beef or mutton fat, and is primarily made up of triglycerides. It is produced by diverse cell types in humans and other animal species. Can react with active metals to form gaseous hydrogen and a metal salt. From these, the alkyds we know today were developed. RTECS # VS0875000 CAS # 111-20-6 See: NMAM or OSHA Methods. The Molecular weight of 202.25. Dicarboxylic acids are also used in the preparation of copolymers such as polyamides and polyesters. Undecylenic acid is mainly used for the production of Nylon-11 and in the treatment of fungal infections of the skin, but it is also a precursor in the manufacture of many pharmaceuticals, personal hygiene products, cosmetics, and perfumes. Fordyce spots are benign, visible, sebaceous glands found usually on the lips, gums and inner cheeks, and genitals. Boiling point: 294.5 °C100 mm Hg. Nonanoic acid, also called pelargonic acid, is an organic compound with structural formula CH3(CH2)7CO2H. EC Number 203-845-5. 5-Hydroxyeicosanoid dehydrogenase (5-HEDH) or more formally, nicotinamide adenine dinucleotide phosphate (NADP+)-dependent dehydrogenase, is an enzyme that metabolizes an eicosanoid product of arachidonate 5-lipoxygenase (5-LOX), 5(S)-hydroxy-6S,8Z,11Z,14Z-eicosatetraenoic acid (i.e. Sebacic acid is a derivative of castor oil. The general molecular formula for dicarboxylic acids can be written as HO2C−R−CO2H, where R can be aliphatic or aromatic. a metabolite of arachidonic acid. All mass spectra in this site (plus many more) are available from the NIST/EPA/NIH Mass Spectral Library. 29, 446 (1952). Skin Contact Wash off immediately with plenty of water for at least 15 minutes. It is a white flake or powdered solid. [6]. Sebacic acid. 5-Oxo-ETE can stimulate various cell types particularly human leukocytes but possesses its highest potency and power in stimulating the human eosinophil type of leukocyte. It contributes to the odor of some rancid oils. Decanedioic acid, compd. Unlike suet, tallow can be stored for extended periods without the need for refrigeration to prevent decomposition, provided it is kept in an airtight container to prevent oxidation. It is an oily liquid with an unpleasant, rancid odor. Educ. C 1 0 H 1 8 O 4. Sapienic acid is a fatty acid that is a major component of human sebum. Organosulfates are a class of organic compounds sharing a common functional group commonly with the structure R-O-SO3−. Human neutrophils can convert sebacic acid to its 5-oxo analog, i.e.5-oxo-6E,8Z-octadecaenoic acid (5-oxo-ODE). February 2006 Molecular Weight. Stearin, or tristearin, or glyceryl tristearate is an odourless, white powder. Ricinoleic Acid Alkali Fusion @ 250 deg C 2-Octanol CH3(CH2)5CH(OH)CH3+ Sebacic Acid COOH(CH2)8COOH+ H2 The process is based on the caustic oxidation of castor oil. Formula Browser Formulas which begin with C 21 H 32 O 4. Hexamethylenediamine sebacate. Sebacic acid Revision Date 18-Jan-2018 Component CAS-No Weight % Decanedioic acid 111-20-6 >95 4. As with some other omega-9 polyunsaturated fatty acids, animals can make Mead acid de novo. [2]. In the eyelids, meibomian glands, also called tarsal glands, are a type of sebaceous gland that secrete a special type of sebum into tears. References. First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Melting point: 133-137 °C. Compound Sebacic acidwith free spectra: 5 NMR, 10 FTIR, and 8 MS. NACRES NA.22 It is an unsaturated fatty acid. It is a secondary eight-carbon chiral compound. - Find MSDS or SDS, a COA, data sheets and more information. It is therefore suggested to be formed during and to be an important contributor to the formation and progression of eosinophil-based allergic reactions; it is also suggested that 5-oxo-ETE contributes to the development of inflammation, cancer cell growth, and other pathological and physiological events. It is a waxy set of lipids composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). Sebacic acid is a saturated, straight-chain naturally occurring dicarboxylic acid: Protocol. Sebacic acid. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Product Name: Sebacic Acid CAS No: 111-20-6 Synonyms: Decanedioic Acid; 1,10-Decanedioic acid 1.2. The esters and salts of nonanoic acid are called nonanoates. It is a precursor to diverse industrial products including polymers and plasticizers, as well as being a component of a number of hair and skin conditioners. We offer Extreme Quality of Sebacic acid. Wego Chemical Group is a long-experienced distributor of Sebacic Acid. Molecular Formula C 10 H 18 O 4; Average mass 202.247 Da; Monoisotopic mass 202.120514 Da; ChemSpider ID 5004; More details: Systematic name. If breathing is difficult, give oxygen. In its pure state, it is a white flake or powdered crystal. An alkyd is a polyester modified by the addition of fatty acids and other components. The type of reaction used affects the purity 106-79-6 - ALOUNLDAKADEEB-UHFFFAOYSA-N - Sebacic acid dimethyl ester - Similar structures search, synonyms, formulas, resource links, and other chemical information. Mead acid is an omega-9 fatty acid, first characterized by James F. Mead. CAS No. 5-Hydroxyeicosatetraenoic acid is an eicosanoid, i.e. For stearin, these melt at 54 (α-form), 65, and 72.5 °C (β-form). Alkyl sulfates consist of a hydrophobic hydrocarbon chain, a polar sulfate group (containing an anion) and either a cation or amine to neutralize the sulfate group. RTECS # VS1150000 ... Molecular Weight. The original alkyds were compounds of glycerol and phthalic acid sold under the name Glyptal. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Many sulfate esters are used in detergents, and some are useful reagents. Sapienic acid is a sebum fatty acid that is unique to humans. Since 5-oxo-ETE is 30-100-fold more potent than 5(S)-HETE in stimulating various cell types, 5-HEDH is regarded as a regulator and promoter of 5(S)HETE's and thereby 5-LOX's influences on cell function. Lithium 12-hydroxystearate is a white solid. It is a waxy solid and its chemical formula is C17H35CO2H. Formula: HOOC(CH2)8COOH. Display Name: Sebacic acid EC Number: 203-845-5 EC Name: Sebacic acid CAS Number: 111-20-6 Molecular formula: C10H18O4 IUPAC Name: decanedioic acid Like other triglycerides, stearin can crystallise in three polymorphs. Beilstein/REAXYS Number 1210591 . Common Name Sebacic Acid Formula C 10 H 18 O 4 CAS Number 111-20-6 COMPONENT CAS NUMBER CONCENTRATION Sebacic Acid 111-20-6 > 99.5% Section 4. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, Registry of Toxic Effects of Chemical Substances (RTECS), U.S. Department of Health & Human Services, lethal concentration (50 percent kill): >4500 mg/m, intraperitoneal/mammal (species unspecified), lethal dose (50 percent kill): 1175 mg/kg, lethal dose (50 percent kill): 14375 mg/kg, Behavioral: Somnolence (general depressed activity), lowest published toxic concentration: 460 µg/m, lowest published toxic concentration: 410 mg/m, Brain and Coverings: Recordings from specific areas of CNS, lowest published toxic dose: 2887 mg/kg/33W- intermittent, National Occupational Exposure Survey 1983, Hazard Code 84426; Number of Industries 17; Total Number of Facilities 1720; Number of Occupations 35; Total Number of Employees Exposed 51959; Total Number of Female Employees Exposed 2762, Hazard Code 84426; Number of Industries 9; Total Number of Facilities 275; Number of Occupations 14; Total Number of Employees Exposed 2129, EPA TSCA Section 8(d) unpublished health/safety studies, EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001. Get medical attention Lithium soaps are key component of many lubricating greases. It has a role as a human metabolite and a plant metabolite. Hexamethylenediammonium sebacate. Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. Ricinoleic acid, formally called 12-hydroxy-9-cis-octadecenoic acid is a fatty acid. Updated. Although 5-HEDH has been evaluated in a wide range of intact cells and in crude microsome preparations, it has not yet been evaluated for its structure, for its gene, of in pure form; furthermore, most studies on it have been conducted in human tissues. Examples include: sodium lauryl sulfate (also known as sulfuric acid mono dodecyl ester sodium salt) and related potassium and ammonium salts. It is a triglyceride derived from three units of stearic acid. Sebacic acid is a white flake or powdered crystal slightly soluble in water that has been proposed as an alternative energy substrate in total parenteral nutrition. As a supplier of Sebacic Acid with a wide distribution network, customers in numerous industries rely on Wego for their supply of Sebacic Acid. Sebacic acid View entire compound with free spectra: 5 NMR, 10 FTIR, and 8 MS. SpectraBase Compound ID: ... 202.25 g/mol: Molecular Formula: C10H18O4: Exact Mass: 202.120509 g/mol: Transmission Infrared (IR) Spectrum. The castor oil is treated with caustic soda at high temperature, e.g. decanedioic acid (ˌdɛkeɪndaɪˈəʊɪk) n (Elements & Compounds) a white crystalline carboxylic acid obtained by heating castor oil with sodium hydroxide, used in the manufacture of polyester resins and rubbers and plasticizers.
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