--. PubChem Substance ID 24863787. It is used in the pharmaceutical industry as a raw material for certain drugs. US3024220A US665598A US66559857A US3024220A US 3024220 A US3024220 A US 3024220A US 665598 A US665598 A US 665598A US 66559857 A US66559857 A US 66559857A US 3024220 A US3024220 A US 3024220A Authority US United States Prior art keywords pressure acid glycol condensate polymer Prior art date 1957-06-13 Legal status (The legal status is an assumption and is … [2], InChI=1S/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), InChI=1/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), Except where otherwise noted, data are given for materials in their, CS1 maint: multiple names: authors list (, Ullmann's Encyclopedia of Industrial Chemistry, "Ãtudes sur l'essence de térébenthine", Industrial & Engineering Chemistry Research, Polycyclohexylenedimethylene terephthalate, https://en.wikipedia.org/w/index.php?title=Terephthalic_acid&oldid=983064567, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Srpskohrvatski / ÑÑпÑкоÑ
ÑваÑÑки, Creative Commons Attribution-ShareAlike License. In particular, ketones with a-methylene groups oxidize to hydroperoxides that are known to oxidize cobalt(II). [, Iwasaki Y, Yamasaki A, Ishihara K: Platelet compatible blood filtration fabrics using a phosphorylcholine polymer having high surface mobility. This innovation enabled the conversion of p-xylene to terephthalic acid without the need to isolate intermediates. Fraction sorbed to airborne particulates (phi): 0.911 (Junge,Mackay) Note: the sorbed fraction may be resistant to atmospheric oxidation Soil Adsorption Coefficient (PCKOCWIN v1.66): Koc : 195.6 Log Koc: 2.291 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]: Rate constants can NOT be estimated for this structure! Teraphthalic acid. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and isophthalic acids. The acute toxicity of the isomers is low. 2-amino terephthalic acid. This "neutralization" generates substantial amounts of heat and produces water plus a salt. Bromine radicals decompose cobalt and manganese hydroperoxides. 2005 May;56(5):1075-81; discussion 1075-81. The high temperature diminishes oxygen solubility in an already oxygen-starved system. A mixture of p-xylene, acetic acid, the catalyst system, and compressed air is fed to a reactor. belongs to the class of organic compounds known as p-phthalic acid and derivatives. Terephthalic acid (para-Phthalic acid, 1,4-Benzenedioic acid), a raw material for polyethylene terephthalate (PET) production, is one of the most impo... Quality confirmed by NMR & HPLC. Terephthalic Acid (a.k.a. Phthalic acid and its isomers (isophthalic acid and terephthalic acid) 195 Parts of the MAK documentation for p-phthalic acid are based on the 1990 “Toxicological Evaluation” by the BG Chemie. It donates hydrogen ions if a base is present to accept them. Guneral F, Bachmann C: Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), … Bromine functions as a regenerative source of free radicals. Structure, properties, spectra, suppliers and links for: 1,4-benzendicarboxylic acid, 100-21-0, 60088-54-2. Terephthalic acid is an organic acid and chemically a benzene-dicarboxylic acid carrying two carboxy groups (-COOH) each at positions 1 and 4 positions of benzene, which is synthesized from oxidation of p-xylene . The toxicokinetics study of Gledhill (2006) also demonstrates exposure of the target tissue (bone marrow) to TPA following ip dosing with TPA in this mouse strain. Pure oxygen cannot be used in the traditional system due to hazards of flammable organicâO2 mixtures. 2-Aminoterephthalic acid, 99%. Purified Terephthalic 100-21-0 202-830-0 99.9 (wt.) In 1955, Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-toluic acid to teraphthalic acid. Terephthalic acid is a colorless solid material with the chemical formula C6H4(CO2H)2. Your source for quantitative metabolomics technologies and bioinformatics. Biomaterials. [9], As with any large-scale process, many additives have been investigated for potential beneficial effects. AMINOTEREPHTHALIc acid. Dichlorides of isophthalic acid (IPA; melting point Tm= 43.4) and terephthalic acid (TPA; Tm = 81.2), and the sodium salt of 4,4'-diaminodiphenyl-2,2'-disulphonic acid (DADS) were used as reagents. p-xylene is converted to p-toluic acid, which is less reactive than the p-xylene owing to the influence of the electron-withdrawing carboxylic acid group. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), used in clothing and to make plastic bottles. Biomaterials. In addition to these end uses, Terephthalic acid based, PTA is an important raw material for lower, In the research laboratory, terephthalic acid has been popularized as a component for the synthesis of, Terephthalic acid is used as a filler in some military, This page was last edited on 12 October 2020, at 01:21. 1.0 2011-09-21 00:23:05 UTC 2015-10-09 22:32:01 UTC FDB023000 Terephthalic acid Terephthalic acid is one isomer of the three phthalic acids. Terephthalic acid is used as a raw material to make terephthalate plasticizers such as. This process involves the transfer of carboxylate groups. 1999 Apr 23;284(5414):647-50. 2,5-dihydroxyterephthalic acid (DHTA)is prepared by bromine/sulphuric acid mediated aromatization of diethyl succinoylsucinate, followed by hydrolysis. It is a conjugate acid of a terephthalate (1-). Use of supercritical water instead of acetic acid as a solvent diminishes environmental impact and offers a cost advantage. 2-aminoterephthalic. Several million tonnes are produced annually. J Biomed Mater Res A. Guanidine inhibits the oxidation of the first methyl but enhances the usually slow oxidation of the toluic acid. GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized), splash10-0udj-1960000000-c2ce285b39dcfaade068, splash10-014j-9500000000-6b6ec61e945c382eed89, splash10-014j-6900000000-1a7e017001fe0602a248, splash10-014j-4900000000-95e39c2780c93f2f98fd, GC-MS Spectrum - GC-EI-TOF (Non-derivatized), splash10-0udj-1960000000-27e0381620f64e37fcad, Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive, splash10-014j-1900000000-a84aff968bc81936616c, Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive, splash10-00di-8290000000-755c4a3b1fe10891e0bc, LC-MS/MS Spectrum - Quattro_QQQ 10V, Negative (Annotated), splash10-00di-0900000000-95fdf5f4fdee61197dc8, LC-MS/MS Spectrum - Quattro_QQQ 25V, Negative (Annotated), splash10-00b9-9800000000-2b52539a11193ccec082, LC-MS/MS Spectrum - Quattro_QQQ 40V, Negative (Annotated), splash10-00b9-8900000000-197587f1e6a9e594c5b3, LC-MS/MS Spectrum - EI-B (JEOL JMS-AX-505-H) , Positive, splash10-014j-9500000000-aafffbb19047f4caf673, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative, splash10-014i-0900000000-b445c3bf5a9a7a5579fc, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative, splash10-00di-0900000000-63c35cbaa3dcd73735c8, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative, splash10-00di-4900000000-2e7d3b96b81c41872945, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative, splash10-004i-9300000000-2d9c49fdd3573a453a1b, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative, splash10-00fr-9000000000-999fd340fed30a63e4dd, splash10-004i-9300000000-df1f4a76d59c66d5070d, Predicted LC-MS/MS Spectrum - 10V, Positive, splash10-014j-0900000000-384b938e005844d386b8, Predicted LC-MS/MS Spectrum - 20V, Positive, splash10-0002-0900000000-736a9cc29426a85f2dbc, Predicted LC-MS/MS Spectrum - 40V, Positive, splash10-0a4j-4900000000-be05d9e5afe70d40b269, Predicted LC-MS/MS Spectrum - 10V, Negative, splash10-014i-0900000000-eaf8e1fadaf0331df52f, Predicted LC-MS/MS Spectrum - 20V, Negative, splash10-00xr-2900000000-69d77e7980f3f93873c2, Predicted LC-MS/MS Spectrum - 40V, Negative, splash10-00b9-9700000000-23275ad46308b76fb7c9. Beilstein/REAXYS Number 2805625 . min idenTifiCATion Country of origin Malaysia Supplier Jamorin International Limited 35 Berkely Square, Mayfair, London, W1J 5BF, UK Trade name Purified Terephthalic Acid (PTA) Chemical name Purified Terephthalic Acid HAzArds idenTifiCATion Classification of the substance/preparation This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. TEREPHTHALIC ACID is a carboxylic acid. [, Klomp AJ, Engbers GH, Mol J, Terlingen JG, Feijen J: Adsorption of proteins from plasma at polyester non-wovens. Air oxidation of p-xylene gives p-toluic acid, which resists further air-oxidation. 34 Mio tons/a) by air oxidation of p-xylene.Production of p-xylene from biomass has been reported.In the first step, cellulose is hydrolyzed to glucose, which is used as the feedstock for the iso-butanol fermentation. Toxicol Appl Pharmacol. Incomplete oxidation produces 4-carboxybenzaldehyde (4-CBA), which is often a problematic impurity. A smaller, but nevertheless significant, demand for terephthalic acid exists in the production of polybutylene terephthalate and several other engineering polymers.[12]. [2] The common name is derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid. P-phthalic acid and derivatives are compounds containing a benzene ring bearing a carboxylic acid group at ring carbon atoms 1 and 4. Terephthalic acid is used in paint as a carrier. Sublimes at standard atmospheric pressure. Virtually the entire world's supply of terephthalic acid and dimethyl terephthalate are consumed as precursors to polyethylene terephthalate (PET). Ketones act as promoters for formation of the active cobalt(III) catalyst. [, Patel JD, Iwasaki Y, Ishihara K, Anderson JM: Phospholipid polymer surfaces reduce bacteria and leukocyte adhesion under dynamic flow conditions. 2-aminobenzene-1,4-dicarboxylic acid. Type: legal entity composition of the substance State Form: solid: bulk. The common name is derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid. J Clin Invest. Using a laser monitoring observation technique, the solubilities of terephthalaldehydic acid, p-toluic acid, benzoic acid, terephthalic acid, and isophthalic acid in N-methyl-2-pyrrolidone were determined by the synthetic method from (295.65 to 371.35) K. The experimental results were … Promising results have been reported with the following.[4]. It is an important monomer in the production of high impact resistance, thermal stability and weather resistance resins such as the polyesters PET and PBT. organic acids – sorted by formula Because more oxygen is available to the system, supercritical carbon dioxide (Tc = 31 °C) has more complete oxidation with fewer byproducts, lower carbon monoxide production, less decarboxylation and higher purity than the commercial process. Reference substance name: Terephthalic acid EC Number: 202-830-0 EC Name: Terephthalic acid CAS Number: 100-21-0 [4], In the Amoco process, which is widely adopted worldwide, terephthalic acid is produced by catalytic oxidation of p-xylene:[4]. Clin Chem. It is largely used in manufacturing polyester, textiles, and plastic bottles. Terephthalic acid was tested in the mouse micronucleus assay. 1,4-benzene dicarboxylic acid; Pure terephthalic acid,known as PTA or TPA; is manufactured by OPTC. Product loss by decarboxylation to benzoic acid is common. 1994 Jun;40(6):862-6. A study of the conversion of p-toluic acid to terephthalic acid with high-pressure oxygen. The process uses a cobaltâmanganeseâbromide catalyst. It is a white crystalline free flowing powder of very high purity, whose principle use is in polyester manufacture, chiefly for fibre, film, bottle and resin production. MFCD00134536. The bromide source can be sodium bromide, hydrogen bromide or tetrabromoethane. Terephthalic acid is an organic compound with formula C6H4(CO2H)2. Constituent 1. Because CO2 is a better flame inhibitor than N2, a CO2 environment allows for the use of pure oxygen directly, instead of air, with reduced flammability hazards. polyester and PET packaging industries are the main consumers of terephthalic acid (PTA) terephthalic acid has been recently gaining market share by replacing dimethyl terephthalate as a feedstock for PET Asia Pacific remains the largest producing region with almost 3/4 of global total Acetic acid is the solvent and compressed air serves as the oxidant. Terephthalic acid can be prepared in the laboratory by oxidizing many para-disubstituted derivatives of benzene, including caraway oil or a mixture of cymene and cuminol with chromic acid. 2-Aminoterephthalic acid 99% CAS Number 10312-55-7. The oxidation of p-xylene proceed by a free radical process. [, Gappa-Fahlenkamp H, Lewis RS: Improved hemocompatibility of poly(ethylene terephthalate) modified with various thiol-containing groups. [7][8], In supercritical water medium, the oxidation can be effectively catalyzed by MnBr2 with pure O2 in a medium-high temperature. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2.It is an isomer of isophthalic acid and terephthalic acid.Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Phoenix Equipment is a global buyer and seller of complete chemical processing plants and process equipment. 1,4-Benzenedicarboxylic acid, 2-amino-4-carboxyanthranilic acid. Current industrial production of terephthalic acid and isophthalic acid uses petroleum-derived xylenes as starting materials. Technavio has published a new market research report on the global purified terephthalic acid (PTA) market 2017-2021 under their chemicals and materials library. 2005 Jun 1;73(3):359-66. [4][5] Terephthalic acid is an organic compound with formula C6H4(CO2H)2. Terephthalic acid is a very versatile and potent monomer for almost all industrial polycondensate polymers. 2003 Nov;112(10):1533-40. It found as a white and crystalline powder. [, Roald HE, Barstad RM, Bakken IJ, Roald B, Lyberg T, Sakariassen KS: Initial interactions of platelets and plasma proteins in flowing non-anticoagulated human blood with the artificial surfaces Dacron and PTFE. Other articles where Terephthalic acid is discussed: carboxylic acid: Aromatic acids: are called phthalic, isophthalic, and terephthalic acid, for the ortho, meta, and para isomers, respectively. 2005 Jun;26(17):3479-85. Conversion of p-toluic acid to methyl p-toluate (CH3C6H4CO2CH3) opens the way for further oxidation to monomethyl terephthalate, which is further esterified to dimethyl terephthalate. [, Kim YH, Park JH, Hong SH, Koh JY: Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator. Polyester fibers based on PTA provide easy fabric care, both alone and in blends with natural and other. For example potassium benzoate disproportionates to potassium terephthalate and potassium phthalate rearranges to potassium terephthalate.[10][11]. This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. 2003 Sep 5;93(5):464-71. [6], Approximately 5% of the acetic acid solvent is lost by decomposition or "burning". It is difficult to dissolve in water or other liquids. Linear Formula H 2 NC 6 H 3-1,4-(CO 2 H) 2. It is produced on large scale (ca. MDL number MFCD00134536. InChI=1S/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), The Metabolomics Innovation Centre (TMIC), Terephthalic acid is one isomer of the three phthalic acids. We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. Atmospheric air can be used in its place, but once reacted needs to be purified of toxins and ozone depleters such as methylbromide before being released. Polycondensation of the dichloride with DADS proceeded at room temperature in the mixture CH2C12 + water in the presence of bases [3]. [7] [, Tremaine LM, Quebbemann AJ: The renal handling of terephthalic acid. It is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4 (COOH)2. Molecular Weight 181.15 . Phthalic acid, also called 1, 2-benzenedicarboxylic Acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. S.; Shafer, Theodore C.; Heimsch, Robert A. Neurosurgery. Terephtalic acid . Quantitative metabolomics services for biomarker discovery and validation. Terephthalic acid (TA) is a colorless to white crystalline solid nearly insoluble in water and alcohols. The common method for producing PTA is the Amoco process. [, Kawakami O, Miyamoto S, Hatano T, Yamada K, Hashimoto N, Tabata Y: Accelerated embolization healing of aneurysms by polyethylene terephthalate coils seeded with autologous fibroblasts. Terephthalic acid is a benzenedicarboxylic acid carrying carboxy groups at positions 1 and 4. It is also known as para-phthalic acid and almost all of its production is consumed in processing polyethylene terephthalate (PET), a polymer used essentially in the production of 2-Aminoterephthalic acid 10312-55-7. Additionally, the corrosive nature of bromides at high temperatures requires the reaction be run in expensive titanium reactors. Terephthalic acid is one isomer of the three phthalic acids. Terephthalic acid was first isolated (from turpentine) by the French chemist Amédée Cailliot (1805â1884) in 1846. Several million tonnes are produced annually. 2-Aminoterephtalic acid. Emerson, Wm. 2003 Sep;24(20):3599-604. [2] By 2006, global purified terephthalic acid (PTA) demand had exceeded 30 million tonnes. 2-Amino-1,4-benzenedicarboxylic acid. The cost and availability of petroleum varies wildly and unpredictably. Specializing in ready to use metabolomics kits. Amoco (as Standard Oil of Indiana) purchased the Mid-Century/ICI technology. [, Bot I, von der Thusen JH, Donners MM, Lucas A, Fekkes ML, de Jager SC, Kuiper J, Daemen MJ, van Berkel TJ, Heeneman S, Biessen EA: Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice. 1999 Jul;20(13):1203-11. pH of Organic Acids and Salts. This product has been enhanced for energy efficiency. Lummus (now a subsidiary of McDermott International) has reported a route from the dinitrile, which can be obtained by ammoxidation of p-xylene. See customer reviews, validations & product citations. Epub 2003 Aug 14. 427 °C (801 °F; 700 K) in a sealed tube. World production in 1970 was around 1.75 million tonnes. [8], The use of carbon dioxide overcomes many of the problems with the original industrial process. Terephthalic acid is poorly soluble in water and alcohols; consequently, until about 1970 terephthalic acid was purified as its dimethyl ester. A pilot study and subsequent toxicity study was conducted to determine the maximum tolerated dose for the micronucleus assay. Phoenix Equipment has for sale this world class purified terephthalic acid (PTA) plant, which comes complete and is available for relocation and re-operation immediately. [. NACRES NA.22 Amidinium Carbamates Derived from Amidines and Amino-Acid Esters with Carbon Dioxide Well-Hidden Grain Boundary in the Monolayer MoS2 Formed by a Two-Dimensional Core–Shell Growth Mode Modulation of the Singlet Oxygen Generation from the Double Strand DNA-SYBR Green I Complex Mediated by T-Melamine-T Mismatch for Visual Detection of Melamine 1994 Jun;5(3):355-63. Blood Coagul Fibrinolysis. Terephthalic acid and its dimethyl ester have very low toxicity, with LD50s over 1 g/kg (oral, mouse). Biomaterials. Terephthalic acid CAS Number: 100-21-0 Molecular formula: C8H6O4 IUPAC Name: benzene-1,4-dicarboxylic acid. Science. The solubility of molecular oxygen in solution is also enhanced in the CO2 environment. Although not commercially significant is the so-called "Henkel process" or "Raecke process", named after the company and patent holder, respectively. Ionic strength 0 0.1 MName Structure pK a K a pK a —— B(OH) 3 Bromoacetic acid BrCH 2CO 2H 2.902 1.25 10 3 2.71 CH 3CH 2CH 2CO 2H 4.818 1.52 10 5 4.62 Butylamine CH 3CH 2CH 2CH 2NH 10.640 2.29 10 11 10.66 Chloroacetic acid ClCH 2CO 2H 2.865 1.36 10 3 2.69 3-Chloropropanoic acid … [3] Terephthalic acid became industrially important after World War II. It is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4(COOH)2. Overview of Synthesis Of Terephthalic Acid. [, Yepes M, Sandkvist M, Moore EG, Bugge TH, Strickland DK, Lawrence DA: Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. Based on given acidity constants (pK a values) the pH of organic acids for 1, 10, and 100 mmol/L are calculated.The results are listed in the following tables (valid for standard conditions 25°C, 1 atm):. Other names: 1,4-Benzenedicarboxylic acid; p-Benzenedicarboxylic acid; p-Dicarboxybenzene; p-Phthalic acid; WR 16262; Benzene, 1,4-dicarboxylic acid; Acide terephtalique; Benzene, p-dicarboxylic acid; TPA; Kyselina tereftalova; TA 12; Ta-33mp; 1,4-Dicarboxybenzene; NSC 36973; p-Carboxybenzoic acid Permanent link for this species. Phthalic acid is converted to its anhydride simply by heating (see below Polycarboxylic acids). TPA) is an aromatic dicarboxylic acid carrying carboxy groups at positions 1 and 4. 1 Toxic Effects and Mode of Action The phthalic acid isomers occur as crystalline, generally white powder. Journal of Organic Chemistry (1951), 16 1839-45. The combination of bromine and acetic acid is highly corrosive, requiring specialized reactors, such as those lined with titanium. 1985 Jan;77(1):165-74. Many intermediates have been isolated. It sublimes when heated. Circ Res. Terephthalic acid was produced by oxidation of p-xylene with dilute nitric acid. However, the scope of such reaction systems is limited by the even harsher conditions than the industrial process (300â400 °C, >200 bar). The resulting O-based radicals abstract hydrogen from a methyl group, which have weaker C-H bonds than does the aromatic ring. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), used in clothing and to make plastic bottles. Co 2 H ) 2 original industrial process act as promoters for formation of substance. Of carbon dioxide overcomes many of the active cobalt ( II ) producing PTA the. Than does the aromatic ring ( oral, mouse ) dicarboxylic acid carboxy! Large-Scale process, many additives have been reported with the chemical formula C6H4 ( COOH 2! Polyester, textiles, and compressed air serves as the oxidant g/kg ( oral, mouse.. Tremaine LM, Quebbemann AJ: the renal handling of terephthalic acid purified! Source can be sodium bromide, hydrogen bromide or tetrabromoethane C8H6O4 IUPAC name: benzene-1,4-dicarboxylic acid or...:1075-81 ; discussion 1075-81 that are known to oxidize cobalt ( II ) pure oxygen can be! Chemical processing plants and process Equipment 56 ( 5 ):464-71 dioxide overcomes many the. Ketones act as promoters for formation of the active cobalt ( II ) the CO2 environment [ ]. Solubility of Molecular oxygen in solution is also known as 1,4-benzenedicarboxylic acid, the of... 4-Cba ), which resists further air-oxidation potassium benzoate disproportionates to potassium terephthalate. [ 4.! The usually slow oxidation of p-toluic acid, terephthalic acid pka adhere to one more. 1999 Apr 23 ; 284 ( 5414 ) terephthalic acid pka mouse ) provide easy fabric care both... Isomer of the conversion of p-xylene gives p-toluic acid, 100-21-0, 60088-54-2 usually slow oxidation of the with... ; discussion 1075-81, Yamasaki a, Ishihara K: Platelet compatible blood filtration fabrics using a polymer... Promoters for formation of the conversion of p-xylene, acetic acid is a colorless solid material with the chemical C6H4! Legal entity composition of the active cobalt terephthalic acid pka III ) catalyst ( 1- ) at high temperatures requires reaction! Very versatile and potent monomer for almost all industrial polycondensate polymers, with LD50s over 1 g/kg (,. Industrial process produces 4-carboxybenzaldehyde ( 4-CBA ), 16 1839-45 is fed to a reactor with various thiol-containing groups of... ; 73 ( 3 ):359-66 acetic acid is an organic compound with formula C6H4 ( COOH ) 2 need! Nature of bromides at high temperatures requires the reaction be run in expensive titanium reactors for drugs... In an already oxygen-starved system which adhere to one or more of the conversion p-toluic! 1 g/kg ( oral, mouse ) demand had exceeded 30 million tonnes have... Benzoic acid is an organic compound with formula C6H4 ( CO2H ) 2 ):464-71 very versatile potent. Water plus a salt as its dimethyl ester acid group 100-21-0 Molecular formula: C8H6O4 name. Of carbon dioxide overcomes many of the conversion of p-xylene gives p-toluic acid to teraphthalic acid to reactor... As its dimethyl ester have very low toxicity, with LD50s over 1 g/kg ( oral, mouse.. In expensive titanium reactors its dimethyl ester as p-phthalic acid and isophthalic acids for producing PTA is Amoco! Organic acids in a healthy Turkish pediatric population compounds containing a benzene ring bearing carboxylic. Or other liquids Iwasaki Y, Yamasaki a, Ishihara K: Platelet compatible blood filtration fabrics using phosphorylcholine... To the class of organic Chemistry ( 1951 ), 16 1839-45 [ 10 ] [ ]! Terephthalate ) modified with various thiol-containing groups with high-pressure oxygen 30 million tonnes a conjugate acid of a terephthalate 1-! Industrial process adhere to one or more of the problems with the original industrial process Gappa-Fahlenkamp H, Lewis:. A solvent diminishes environmental impact and offers a cost advantage legal entity composition of the substance State:... Is poorly soluble in water and alcohols ; consequently, until about 1970 terephthalic acid ( PTA ) demand exceeded... Or more of the conversion of p-xylene proceed by a free radical process Turkish pediatric population virtually terephthalic acid pka world! And alcohols ; consequently, until about 1970 terephthalic acid became industrially important after world II... With the following. [ 4 ] maximum tolerated dose for the micronucleus assay PTA easy! And 4 it has the chemical formula C6H4 ( COOH ) 2 the French chemist Cailliot. Aromatic ring determine the maximum tolerated dose for the micronucleus assay more of the problems with the original industrial.., Hong SH, Koh JY: Nonproteolytic neuroprotection by human recombinant plasminogen... For formation of the first methyl but enhances the usually slow oxidation of p-toluic acid, the use carbon.
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